Saliva Drug Testing Kits

May 13, 2016

The Saliva Multi-Drug Test is a one-step lateral flow
chromatographic immunoassay based on the principle of competition for
limited antibody binding sites between the drug in the sample and a
drug-protein conjugate immobilized on a porous membrane support.
During testing, saliva migrates to the testing area of the membrane by
capillary action, mobilizing the colored antibody conjugates. The antibody
conjugates then move along the membrane to the test area. In the
absence of drug, or if the drug concentration in oral fluid is below the
cutoff limit, the colored conjugates attach to the respective drug antigen
immobilized in the test line region, forming a colored band (T line). If
drug is present in oral fluid, the drug competes for limited antibody
binding sites. If the drug concentration is at or above the cutoff limit, the
drug will saturate all the binding sites of the antibody, preventing the
attachment of the colored conjugates to the antigen in the test line area
of the membrane.


This test is capable of detecting specific drugs and/or drug metabolites in
human oral fluid at or above the cutoff concentrations indicated in the
Intended Use section.

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